Most compounded GLP-1 programs are cash-pay by design, and many brand-name options have self-pay routes too. Here's what to expect when you're paying out of pocket.
Compounded tirzepatide is typically cash-pay (often HSA/FSA-eligible) and runs $186–$400/month — lower than brand-name, but not FDA-approved. Brand-name self-pay: Eli Lilly's LillyDirect offers self-pay Zepbound vials that are lower than pharmacy retail list for some doses. Pharmacy retail without coverage is the most expensive route (~$1,000+/month).
Compare on the full price guide; for the compounded vs brand trade-off see Zepbound vs compounded.